Answer by iBet7o for Remove empty array elements

Remove empty array elements

function removeEmptyElements(&$element)
{
    if (is_array($element)) {
        if ($key = key($element)) {
            $element[$key] = array_filter($element);
        }

        if (count($element) != count($element, COUNT_RECURSIVE)) {
            $element = array_filter(current($element), __FUNCTION__);
        }

        return $element;
    } else {
        return empty($element) ? false : $element;
    }
}

$data = array(
    'horarios' => array(),
    'grupos' => array(
        '1A' => array(
            'Juan' => array(
                'calificaciones' => array(
                    'Matematicas' => 8,
                    'Español' => 5,
                    'Ingles' => 9,
                ),
                'asistencias' => array(
                    'enero' => 20,
                    'febrero' => 10,
                    'marzo' => '',
                )
            ),
            'Damian' => array(
                'calificaciones' => array(
                    'Matematicas' => 10,
                    'Español' => '',
                    'Ingles' => 9,
                ),
                'asistencias' => array(
                    'enero' => 20,
                    'febrero' => '',
                    'marzo' => 5,
                )
            ),
        ),
        '1B' => array(
            'Mariana' => array(
                'calificaciones' => array(
                    'Matematicas' => null,
                    'Español' => 7,
                    'Ingles' => 9,
                ),
                'asistencias' => array(
                    'enero' => null,
                    'febrero' => 5,
                    'marzo' => 5,
                )
            ),
        ),
    )
);

$data = array_filter($data, 'removeEmptyElements');
var_dump($data);

¡it works!